Arsenal coasted to a 3-1 win over AC Milan on Thursday night using a 4-3-3 formation to ensure qualification to the last eight of the competition, but will Wenger look to continue with that system?
The Gunners have used a number of different set-ups this term as he tries to get the best out of his squad in different outings, and injuries have often been a catalyst to those changes, but with Jack Wilshere and Aaron Ramsey both fighting fit and in-form, it is hard to deny either a starting berth.
There has only been limited opportunities to play both in a first-team capacity since the pair have both suffered with injury setbacks this season as well as in previous years, but the duo did both start against Milan on Thursday night, and it could be interesting to see that system furthered.
Granit Xhaka is the player tasked with bringing the extra defensive stability to free up either midfielder in a central pairing, and he would likely continue to play in the middle of the three to allow the creativity of the homegrown stars to push forward and help out in attack.
Alex Iwobi would likely be the player to lose out most on action, with Henrikh Mkhitaryan and Mesut Ozil’s place in the line-up not in question, and that midfield should create a large number of chances for whoever gets the nod up front between Alexandre Lacazette and Pierre-Emerick Aubameyang.
Should Wenger stick with a midfield three? Could Wilshere be fielded further up the field?