This is a game that Arsenal really has to win and Mikel Arteta also needs a win desperately or the pressure on him will start to increase significantly.
There are injuries galore and of course, there was no chance of Gabriel Martinelli featuring which will lift one cloud hanging over Arteta.
Southampton will definitely be feeling confident and a win for them will see them go level on points with Arsenal and if Burnley beat Watford then a loss for the Gunners could see them drop to 12th in the standings.
This is the team that Arteta is going with to avoid that scenario unfolding.
Is this line up good enough to secure all three points today? Let us know in the comments below.
Links to streams will be put in the comments where to watch the game live and free so keep checking in.
Also, if you go to the official Arsenal website here you will be able to get live commentary text and radio.
JustArsenal predicted line up (for comparison) here
JustArsenal match preview here